J John Mann Selected Research

5-HT1A Serotonin Receptor

12/2022	Brain 5-HT1A Receptor PET Binding, Cortisol Responses to Stress, and the Familial Transmission of Suicidal Behavior.
10/2022	Ventral prefrontal serotonin 1A receptor binding: a neural marker of vulnerability for mood disorder and suicidal behavior?
1/2022	Serotonin 1A Receptor Binding of [11C]CUMI-101 in Bipolar Depression Quantified Using Positron Emission Tomography: Relationship to Psychopathology and Antidepressant Response.
1/2019	Cortisol Stress Response and in Vivo PET Imaging of Human Brain Serotonin 1A Receptor Binding.
7/2018	In vivo relationship between serotonin 1A receptor binding and gray matter volume in the healthy brain and in major depressive disorder.
2/2015	Positron emission tomography quantification of serotonin(1A) receptor binding in suicide attempters with major depressive disorder.
7/2014	Genetic variation in brain-derived neurotrophic factor val66met allele is associated with altered serotonin-1A receptor binding in human brain.
11/2013	Brain serotonin 1A receptor binding as a predictor of treatment outcome in major depressive disorder.
11/2013	Higher pretreatment 5-HT1A receptor binding potential in bipolar disorder depression is associated with treatment remission: a naturalistic treatment pilot PET study.
9/2007	PET tracers for 5-HT(1A) receptors and uses thereof.

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J John Mann Research Topics

Disease

58	Major Depressive Disorder (Major Depressive Disorders) 08/2022 - 05/2003
26	Mood Disorders (Mood Disorder) 12/2022 - 08/2004
25	Bipolar Disorder (Manic Depressive Psychosis) 01/2022 - 05/2003
16	Schizophrenia (Dementia Praecox) 11/2019 - 04/2002
16	Alcoholism (Alcohol Abuse) 01/2019 - 01/2003
14	Mental Disorders (Mental Disorder) 01/2017 - 04/2002
7	Inflammation (Inflammations) 01/2022 - 01/2016
7	Alzheimer Disease (Alzheimer's Disease) 05/2021 - 09/2007
6	Brain Diseases (Brain Disorder) 05/2021 - 03/2009
6	Disease Progression 01/2019 - 03/2009
6	Depressive Disorder (Melancholia) 01/2018 - 05/2003
6	Anxiety Disorders (Anxiety Disorder) 01/2018 - 12/2004
5	Neoplasms (Cancer) 10/2020 - 08/2014
5	Substance-Related Disorders (Drug Abuse) 01/2017 - 01/2003
4	Disease Susceptibility (Diathesis) 12/2014 - 10/2007
4	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 03/2013 - 10/2004
4	Borderline Personality Disorder (Personality Disorders, Borderline) 02/2012 - 07/2003
3	Syndrome (Syndromes) 01/2022 - 04/2005
3	Neuroinflammatory Diseases 05/2021 - 01/2018
3	Parkinson Disease (Parkinson's Disease) 05/2021 - 09/2007
3	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2020 - 11/2006
3	Nervous System Diseases (Neurological Disorders) 02/2019 - 10/2014
3	Cognitive Dysfunction 01/2017 - 09/2010
3	Psychotic Disorders (Schizoaffective Disorder) 10/2016 - 09/2003
2	Fatigue 01/2022 - 11/2014
2	Encephalitis (Encephalitis, Rasmussen) 01/2022 - 01/2022
2	Stroke (Strokes) 05/2021 - 12/2018
2	Epilepsy (Aura) 05/2021 - 09/2007
2	Arthritis (Polyarthritis) 12/2018 - 08/2018
2	Mania (Manias) 01/2018 - 10/2012
2	Antisocial Personality Disorder (Antisocial Personality) 01/2017 - 08/2005
2	Personality Disorders (Personality Disorder) 01/2017 - 09/2003
2	Dementia (Dementias) 01/2017 - 04/2008
2	Pain (Aches) 01/2017 - 07/2010

Drug/Important Bio-Agent (IBA)

32	Serotonin (5 Hydroxytryptamine)IBA 08/2022 - 04/2003
20	Antidepressive Agents (Antidepressants)IBA 01/2022 - 07/2003
13	Biological ProductsIBA 12/2014 - 07/2005
12	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 08/2022 - 11/2004
10	5-HT1A Serotonin ReceptorIBA 12/2022 - 09/2007
9	Proteins (Proteins, Gene)FDA Link 11/2019 - 04/2002
9	Biomarkers (Surrogate Marker)IBA 12/2018 - 12/2007
7	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2022 - 10/2004
7	Pharmaceutical PreparationsIBA 10/2019 - 03/2005
6	Ketamine FDA LinkGeneric 01/2022 - 01/2017
6	Neurotransmitter Agents (Neurotransmitter)IBA 11/2019 - 04/2004
6	SNARE Proteins (SNAREs)IBA 11/2019 - 04/2002
6	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 10/2019 - 01/2011
6	N- (2- (4- (2- methoxyphenyl)- 1- piperazinyl)ethyl)- N- (2- pyridinyl)cyclohexanecarboxamideIBA 01/2019 - 08/2009
6	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 10/2016 - 11/2004
6	Norepinephrine (Noradrenaline)FDA LinkGeneric 09/2013 - 04/2004
5	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2022 - 12/2018
5	AutoreceptorsIBA 01/2018 - 05/2004
5	Dopamine (Intropin)FDA LinkGeneric 01/2017 - 04/2004
5	3,4-methylenedioxyethamphetamine (MDEA)IBA 09/2013 - 09/2003
4	EnzymesIBA 05/2021 - 07/2010
4	Eicosapentaenoic AcidIBA 01/2021 - 03/2014
4	FenfluramineIBA 03/2014 - 05/2003
4	AcidsIBA 01/2014 - 09/2004
4	Glucose (Dextrose)FDA LinkGeneric 09/2010 - 11/2004
3	Midazolam (Versed)FDA LinkGeneric 01/2022 - 01/2017
3	Testosterone (Sustanon)FDA Link 01/2022 - 10/2012
3	Phospholipids (Phosphatides)FDA LinkGeneric 01/2021 - 03/2014
3	Docosahexaenoic AcidsIBA 01/2021 - 03/2014
3	Arachidonic Acid (Vitamin F)IBA 01/2021 - 03/2014
3	Glutamic Acid (Glutamate)FDA Link 01/2021 - 11/2011
3	Serotonin ReceptorsIBA 02/2019 - 01/2014
3	Antipsychotic Agents (Antipsychotics)IBA 02/2017 - 05/2006
3	Qa-SNARE Proteins (Syntaxin)IBA 11/2016 - 04/2010
3	Bupropion (Wellbutrin)FDA LinkGeneric 02/2015 - 09/2013
3	Dexamethasone (Maxidex)FDA LinkGeneric 08/2006 - 10/2004
3	Homovanillic AcidIBA 03/2005 - 09/2003
2	EsketamineIBA 01/2022 - 01/2022
2	Interleukin-6 (Interleukin 6)IBA 10/2021 - 01/2021
2	Indicators and Reagents (Reagents)IBA 01/2021 - 12/2018
2	Glutamate Receptors (Glutamate Receptor)IBA 01/2021 - 02/2013
2	Lurasidone Hydrochloride FDA Link 01/2021 - 01/2017
2	Synaptosomal-Associated Protein 25IBA 11/2019 - 09/2015
2	3-N-(2-fluoroethyl)spiperone (FESP)IBA 10/2019 - 10/2016
2	Risperidone (Risperdal Consta)FDA LinkGeneric 10/2019 - 10/2016
2	LipidsIBA 10/2018 - 06/2017
2	LigandsIBA 05/2018 - 07/2014
2	Monoamine Oxidase (MAO)IBA 01/2018 - 08/2004
2	Protein Isoforms (Isoforms)IBA 01/2018 - 11/2016
2	Fish OilsIBA 01/2017 - 12/2011
2	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2017 - 07/2009
2	CytokinesIBA 01/2016 - 10/2011
2	Paroxetine (Paxil)FDA LinkGeneric 02/2015 - 09/2013
2	BenzodiazepinesIBA 12/2014 - 10/2014
2	gamma-Aminobutyric Acid (GABA)IBA 10/2014 - 06/2002
2	Tryptophan (L-Tryptophan)FDA Link 08/2014 - 03/2009
2	KynurenineIBA 08/2014 - 08/2011
2	ProlactinIBA 03/2014 - 05/2003
2	Hydroxyindoleacetic AcidIBA 03/2014 - 10/2006
2	Fluoxetine (Prozac)FDA LinkGeneric 06/2012 - 06/2012
2	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 06/2012 - 06/2012
2	Tryptophan HydroxylaseIBA 02/2012 - 03/2009
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 11/2011 - 11/2006
2	LithiumIBA 10/2011 - 12/2009

Therapy/Procedure

7	Therapeutics 01/2019 - 11/2010
4	Drug Therapy (Chemotherapy) 01/2014 - 09/2004